2024

• TM-catalyzed reaction

  Stereospecific and Stereodivergent Allyl-Allyl Coupling: Construction of Vicinal Tertiary and All-Carbon Quaternary Stereocenters

  Yongsuk Jung+, Jieun Kim+, Gwanggyun Kim, Jiyeon Ko, Sungwoo Hong*, and Seung Hwan Cho* (+These authors contributed equally to this work) 

  ACS Catal. 2024, 14, 18660-18668. 

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• TM-catalyzed reaction

  Copper-Catalyzed Regio-, Diastereo- and Enantioselective Allylic Alkylation with 1,1-Diborylalkanes

  Minjae Kim, Gwanggyun Kim, Doyoon Kim, Seung Hwan Cho*

  J. Am. Chem. Soc. 2024, 146, 34861-34869. 

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• TM-free reaction

  Diverse Synthesis of (Thio)ethers and (Thio)esters Using Halodiborylmethane as a Transformable C1 Building Block

  Chiwon Hwang+, Yunhui Jang+, Yongsuk Jung, Jaeyoon Seo, Kwangmin Shin, and Seung Hwan Cho* (+These authors contributed equally to this work) 
  

  Org. Lett. 2024, 26, 7010-7014. 

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• TM-free reaction

  Axially Chiral α-Boryl-Homoallenyl Boronic Esters as Versatile Toolbox for Accessing Centrally and Axially Chiral Molecules

  Yonghoon Jin, Junseok Lee, Woohyun Jo, Jeongwoo Yu, and Seung Hwan Cho* 

  Nat. Commun. 2024, 15, 9239. 

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2023

• TM-free reaction

  Anion-Mediated, Stereospecific Synthesis of Secondary and Tertiary Cyclopropylboronates from Chiral Epoxides and gem-Diborylalkanes

  Gwanggyun Kim+, Minjae Kim,+ Changsu Ryu, Juhyeok Choi, Seung Hwan Cho* (+These authors contributed equally to this work) 

  Org. Lett. 2023, 25, 4130-4134. 

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• TM-catalyzed reaction

  Iridium-Catalyzed Chemo-, Diastereo-, and Enantioselective Allyl–Allyl Coupling: Accessing All Four Stereoisomers of (E)-1-Boryl-Substituted 1,5-Dienes by Chirality Pairing

  Yongsuk Jung+, Seok Yeol Yoo+, Yonghoon Jin, Jaehyun Yu, Seungcheol Han, Jeongwoo Yu, Yoonsu Park,* Seung Hwan Cho* (+These authors contributed equally to this work) 

  Angew. Chem. Int. Ed. 2023, 62, e202218794. 

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• TM-free reaction

  Chemo-, Regio-, and Stereoselective Access to (E)-Boryl-Substituted Allyl Fluorides via Electrophilic Fluorodesilylation

  Yongsuk Jung, Seung Hwan Cho* 

  Synlett 2023, 34, 2165-2168. 

  [Special issue on “Modern Organoboron Chemistry: 60 Years of the Matteson Reaction”]​

  Highlighted in Organic Chemistry Portal

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2022

• TM-free reaction

  Stereoselective Access to Tetra- and Tri-substituted Fluoro- and Chloro-borylalkenes via Boron-Wittig Reaction

  Seungcheol Han, Yeosan Lee, Yujin Jung, Seung Hwan Cho*  

  Angew. Chem. Int. Ed. 2022, 61, e202210532.

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• TM-free reaction

  Diborylmethyl Group as a Transformable Building Block for the Diversification of Nitrogen-Containing Molecules

  Chiwon Hwang+, Yeosan Lee+, Minjae Kim, Younggyu Seo, Seung Hwan Cho* (+These authors contributed equally to this work) 

  Angew. Chem. Int. Ed. 2022, 61, e202209079.
  [Selected as “Very Important Paper (VIP)”] 

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• Others

  Combinatorial selective synthesis and excitation experiments for quantitative analysis of the effects of Au on a semiconductor photocatalyst

  Yongdeok Ahn, Jiseong Park, Minsoo Park, Siwoo Jin, Woohyun Jo, Jeongho Kim, Seung Hwan Cho, Daeha Seo* 

  Chem, 2022, 8, 2485-2497. 

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• TM-free reaction

  Defluorinative C–C Bond-Forming Reaction of Trifluoromethyl Alkenes with (gem-Diborylalkyl)lithiums

  Haeun Kim+, Yujin Jung+, Seung Hwan Cho* (+These authors contributed equally to this work) 

  Org. Lett. 2022, 24, 2705-2710.  

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2021

• Review paper

  Catalytic Chemo- and Enantioselective Transformations of gem-Diborylalkanes and (Diborylmethyl)metallic Species

  Yeosan Lee, Seungcheol Han, Seung Hwan Cho* 

  Acc. Chem. Res. 2021, 54, 3917-3929. 

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• Review paper

  Advances in Transition Metal-Free Deborylative Transformations of gem-Diborylalkanes

  Woohyun Jo, Jun Hee Lee*, Seung Hwan Cho* 

  Chem. Commun. 2021, 27, 4246-4353. 

  [Review: Invited Feature Article]

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• TM-catalyzed reaction

  Copper-Catalyzed Enantiotopic-Group-Selective Allylation of gem-Diborylalkanes

  Minjae Kim+, Bohyun Park+, Minkyeong Shin, Suyeon Kim, Junghoon Kim, Mu-Hyun Baik,* Seung Hwan Cho* (+These authors contributed equally to this work)
  J. Am. Chem. Soc. 2021, 143, 1069-1077.
  Highlighted in Synfacts, 2021, 17, 0292. 

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• TM-free reaction

  Kinetic Resolution of α-Silyl-Substituted Allylboronate Esters via Chemo- and Stereoselective Allylboration of Aldehydes

  Jinyoung Park, Yongsuk Jung, Jeongho Kim, Eunsung Lee, Sarah Yunmi Lee, Seung Hwan Cho*
  Adv. Synth. Cat. 2021, 363, 2371-2376.
  [Special issue on "Boron in Catalysis and Organic Synthesis"]
  [Selected as "Very Important Publication (VIP)"]
  [Selected as "Front Cover"] 

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• TM-catalyzed reaction

  Pd‐Catalyzed Negishi Cross‐Coupling of Vinyl Bromides with Diborylmethylzinc Chlorides

  Minjae Kim, Seungyeol BaekJun Hee Lee*, Seung Hwan Cho* 

  Bull. Kor. Chem. Soc.. 2021, 42, 499-501.

  [Special issue on "Chemical Synthesis & Reaction Development"] 

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2020

• TM-free reaction

  ZnMe2-Mediated, Direct Alkylation of Electron Deficient N-Heteroarenes with 1,1-Diborylalkanes: Scope and Mechanism

  Woohyun Jo, Seungyeol Baek, Chiwon Hwang, Joon Heo, Mu-Hyun Baik,* Seung Hwan Cho* 

  J. Am. Chem. Soc. 2020, 142, 13235-13245. 

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• Others

  Cobalt-Catalyzed Defluorosilylation of Aryl Fluorides via Grignard Reagent Formation

  Soobin Lim, Hyungdo Cho, Jongheon Jeong, Minjae Jang, Hyunseok Kim, Seung Hwan Cho, Eunsung Lee* 

  Org. Lett. 2020, 22, 7387-7392 

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• TM-catalyzed reaction

  Facile Synthesis of a-Boryl-Substituted Allylboronate Esters Using Stable 1,1-Bis[(pinacolato)boryl]methylzinc Halides

  Minkyeong Shin, Minjae Kim, Chiwon Hwang, Hyojae Lee, Hyunchul Kwon, Jinyoung Park, Eunsung Lee, Seung Hwan Cho* 

  Org. Lett. 2020, 22, 2476-2480. 

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• Others

  Highly Mesoporous Metal Organic Frameworks as Synergistic Multimodal Catalytic Platforms for Divergent Cascade Reactions

  Soumen Dutta, Nitee Kumari, Sateesh Dubbu, Sun Woo Jang, Amit Kumar, Hiroyoshi Ohtsu, Junghoon Kim, Seung Hwan Cho, Masaki Kawano, In Su Lee* 

  Angew. Chem., Int. Ed. 2020, 59, 3416-3422. 

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2019

• TM-catalyzed reaction

  Copper-Catalyzed Diastereo- and Enantioselective Addition of 1,1-Diborylalkanes to Cyclic Ketimines and α-Imino Esters

  Jeongho Kim, Minkyeong Shin, Seung Hwan Cho*  

  ACS Catal. 2019, 9, 8503-8508. 
  Highlighted in Synfacts, 2019, 15, 1281. 

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• TM-catalyzed reaction

  Palladium-Catalyzed Chemoselective Negishi Cross-Coupling of Bis[(pinacolato)boryl]methyl Zinc Halides with Aryl (Pseudo)Halides

  Hyojae Lee, Yeosan Lee, Seung Hwan Cho* 

  Org. Lett. 2019, 21, 5912-5916. 

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• TM-catalyzed reaction

  Chemoselective Palladium-Catalyzed Suzuki-Miyaura Cross-Coupling of (Diborylmethyl)silanes with Alkenyl Bromides

  Junghoon Kim, Eunsung Lee, Seung Hwan Cho* 

  Asian J. Org. Chem. 2019, 8, 1664-1667.
  [Special issue on "Researchers in Korea"] 

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• TM-catalyzed reaction

  Access to Enantioenriched Benzylic 1,1-Silylboronate Esters by Palladium-Catalyzed Enantiotopic-Group Selective Suzuki-Miyaura Coupling of (Diborylmethyl)silanes with Aryl Iodides

  Junghoon Kim, Seung Hwan Cho* 

  ACS Catal. 2019, 9, 230-235. 

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• TM-catalyzed reaction

  Improved Synthesis of β-Aminoboronate Esters via Copper-Catalyzed Diastereo- and Enantioselective Addition of 1,1-Diborylalkanes to Acyclic Arylaldimines

  Jeongho Kim,+ Chiwon Hwang,+ Youngmin Kim, Seung Hwan Cho* (+ These authors contribute equally to this work) 

  Org. Process Res. Dev. 2019, 23, 1663-1668.
  [Special issue on "Honoring 25 Years of the Buchwald-Hartwig Amination"] 

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2018

• TM-catalyzed reaction

  Generation and Application of (Diborylmethyl)zinc(II) Species: Access to Enantioenriched gem-Diborylalkanes by an Asymmetric Allylic Substitution” Angew. Chem., Int. Ed. 2018, 57, 12930-12934

  Yeosan Lee, Jinyoung Park, Seung Hwan Cho* 

  Angew. Chem., Int. Ed. 2018, 57, 12930-12934.
  Highlighted in Synfacts, 2018, 14, 1164. 

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2017

• TM-free reaction

  Chemo- and Stereoselective Crotylation of Aldehydes and Cyclic Aldimines with Allylic-gem-diboronate Ester

  Jinyoung Park, Seoyoung Choi, Yeosan Lee, Seung Hwan Cho* 

  Org. Lett. 2017, 19, 4054-4057. 

  Detail view +
  

• TM-catalyzed reaction

  Diastereo- and Enantioselective Synthesis of b-Aminoboronate Esters by Copper(I)-Catalyzed 1,2-Addition of 1,1-Bis[(pinacolato)boryl]alkanes to Imines

  Jeongho Kim, Kwangwook Ko, Seung Hwan Cho* 

  Angew. Chem., Int. Ed. 2017, 56, 11584-11588.
  Highlighted in Synfacts, 2017, 13, 959. 

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• TM-free reaction

  Base-promoted, Deborylative Secondary Alkylation of N-Heteromatic N-Oxides with Internal gem-Bis[(pinacolato)boryl)]alkanes: A Facile Derivatization of 2,2′-Bipyridyl Analogues

  Chiwon Hwang, Woohyun Jo, Seung Hwan Cho* 

  Chem. Commun. 2017, 53, 7573-7576. 

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• TM-free reaction

  Chemoselective Coupling of 1,1-Bis[(pinacolato)boryl]alkanes for the Transition-Metal-Free Borylation of Aryl and Vinyl Halides: A Combined Experimental and Theoretical Investigation

  Yeosan Lee,+ Seung-yeol Baek,+ Jinyoung Park, Seoung-Tae Kim, Samat Tussupbayev, Jeongho Kim, Mu-Hyun Baik,* Seung Hwan Cho* (+These authors contributed equally to this work) 

  J. Am. Chem. Soc. 2017, 139, 976-984. 

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• Others

  Concave Silica Nanosphere with a Functionalized Open-Mouthed Cavity as Highly Active and Durable Catalytic Nanoreactor

  Jin Goo Kim, Amit Kumar, Seung Jin Lee, Junghoon Kim, Dong-Gyu Lee, Taewan Kwon, Seung Hwan Cho, In Su Lee* 

  Chem. Mater. 2017, 29, 7785-7793. 

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• Others

  Confined Nucleation and Growth of PdO Nanocrystals in a Seed-Free Solution inside Hollow Nanoreactor

  Daun Kim, Jung Kyu Choi, Soo Min Kim, Ilha Hwang, Jaehyoung Koo, Seoyoung Choi, Seung Hwan Cho, Kimoon Kim*, In Su Lee* 

  ACS Appl. Mater. Interfaces, 2017, 9, 29992-30001. 

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• Others

  Spontaneous Pt Deposition on Defective Surfaces of In2O3 Nanocrystals Confined within Cavities of Hollow Silica Nanoshells: Pt Catalyst-Modified ITO Electrode with Enhanced ECL Performance

  Young Shin Cho, Soo Min Kim, Youngwon Ju, Junghoon Kim, Ki-Wan Jeon, Seung Hwan Cho, Joohoon Kim, In Su Lee* 

  ACS Appl. Mater. Interfaces, 2017, 9, 20728-20737. 

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2016

• Review paper

  Recent Developments in the Direct Methylation of Electron Deficient N-Heteroarenes

  Junghoon Kim, Seung Hwan Cho* 

  Synlett, 2016, 27, 2525-2529.
  [Mini Review: Invited Synpact article] 

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• TM-free reaction

  Transition-Metal-Free Regioselective Alkylation of Pyridine N-Oxides Using 1,1-Diborylalkanes as Alkylating Reagents

  Woohyun Jo+, Junghoon Kim+, Seoyoung Choi, Seung Hwan Cho* (+ These authors contribute equally to this work) 

  Angew. Chem., Int. Ed. 2016, 55, 9690-9694.
  Highlighted in Synfacts 2016, 12, 1016. 

  Detail view +
  

• TM-catalyzed reaction

  Copper-Catalyzed Diastereoselective Addition of Diborylmethane to N–tert-butanesulfinyl Aldimines: Synthesis of b-Aminoboronates

  Jinyoung Park, Yeosan Lee, Junghoon Kim, Seung Hwan Cho* 

  Org. Lett. 2016, 18, 1210-1213.
  Highlighted in Synfacts, 2016, 12, 503. 

  Detail view +
  

• TM-catalyzed reaction

  Synthesis of Branched Alkylboronates by Copper-Catalyzed Allylic Substitution Reactions of Allylic Chlorides with 1,1-Diborylalkanes

  Junghoon Kim, Sangwoo Park, Jinyoung Park, Seung Hwan Cho* 

  Angew. Chem., Int. Ed. 2016, 55, 1498-1501. 

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• Others

  Iridium-Catalyzed, Hydrosilyl-Directed Borylation of Unactivated Alkyl C-H Bonds

  Matthew Larsen, Seung Hwan Cho, John F. Hartwig* 

  J. Am. Chem. Soc. 2016, 138, 762-765. 

  Highlighted in Synfacts, 2016, 12, 371. 

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BEFORE 2016

• Others

  Iridium-catalyzed Diborylation Directed by a Hydrosilyl Group: Synthesis of 1,1-benzyldiboronate esters

  Seung Hwan Cho, John F. Hartwig* 

  Chem. Sci. 2014, 5, 694-698.  

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• Others

  Iridium-catalyzed Borylation of Secondary Benzylic C-H Bonds Directed by Hydrosilane

  Seung Hwan Cho, John F. Hartwig* 

  J. Am. Chem. Soc. 2013, 135, 8157-8160.(Highlighted in Synfacts, 2013, 9, 880.) 

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• Others

  Rhodium-Catalyzed Intermolecular Amidation of Arenes with Sulfonyl Azides via Chelation-Assisted C-H bond

  Ji Young Kim, Sehume, Park, Jaeyune, Ryu, Seung Hwan Cho, Seok Hwan Kim, Sukbok Chang* 

  J. Am. Chem. Soc. 2012, 134, 9110-9113. 

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• Others

  A Versatile Rh(I) Catalyst System Enabling the Addition of Heteroarenes to both Alkenes and Alkynes via C-H Bond Activation Pathway

  Jaeyune, Ryu, Seung Hwan Cho*, Sukbok Chang* (*Co-corresponding authors: Cho & Chang) 

  Angew. Chem., Int. Ed. 2012, 51, 3677-3681. (“Hot Paper & Selected paper in Cheminform“) 

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• Others

  Intramolecular Oxidative Diamination and Aminohydroxylation of Olefins under Metal-Free Conditions

  Hyun Jin Kim, Seung Hwan Cho, Sukbok Chang* 

  Org. Lett. 2012, 14, 1424-1427. 

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• Others

  Intermolecular Oxidative C−N Bond Formation under Metal-Free Conditions: Control of Chemoselectivity between Aryl sp2 and Benzylic sp3 C−H Bond Imidation

  Hyun Jin Kim, Jiyu Kim, Seung Hwan Cho,* Sukbok Chang* (*Co-corresponding authors: Cho & Chang) 

  J. Am. Chem. Soc. 2011, 133, 16382-16385. 

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• Others

  Recent Advances in the Transition Metal-Catalyzed Twofold Oxidative C–H Bond Activation Strategy for C–C and C–N Bond Formation

  Seung Hwan Cho, Ji Young Kim, Jaesung Kwak, Sukbok Chang* 

  Chem. Soc. Rev. 2011, 40, 5068-5083. 

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• Others

  Intramolecular Oxidative C-N Bond Forming Reaction for the Synthesis of Carbazoles: Comparison of Reactivity between the Cu-Catalyzed and Metal-Free Conditions

  Seung Hwan Cho, Jungho Yoon, Sukbok Chang* 

  J. Am. Chem. Soc. 2011, 133, 5996-6005. 

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• Others

  Cobalt- and Manganese-Catalyzed Direct Amination of Azoles under Highly Mild Conditions

  Ji Young Kim, Seung Hwan Cho, Jomy Joseph, Sukbok Chang* 

  Angew. Chem., Int. Ed. 2010, 49, 9899-9903. 

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• Others

  Silver-Mediated Direct Amination of Benzoxazoles: Tuning the Amino Group Source from Formamides to Parents Amines

  Seung Hwan Cho, Ji Young Kim, S. Yunmi Lee, Sukbok Chang* 

  Angew. Chem., Int. Ed. 2009, 48, 9127-9130. (“Hot Paper“) 

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• Others

  Synthesis of Condensed Pyrroloindoles via Pd-Catalyzed Intramolecular C–H Bond Functionalization of Pyrroles

  Seung Jun Hwang, Seung Hwan Cho, Sukbok Chang* 

  J. Am. Chem. Soc. 2008, 130, 16158-16159. 

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• Others

  Palladium-Catalyzed C–H Functionalization of Pyridine N-Oxides: Highly Selective Alkenylation and Direct Arylation with Unactivated Arenes

  Seung Hwan Cho, Seung Jun Hwang, Sukbok Chang* 

  J. Am. Chem. Soc. 2008, 130, 9254-9256. (“One of the Top most cited JACS articles within last 3 years: July, 2008 ~ July, 2011“) 

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• Others

  Cu-Facilitated C–O Bond Formation Using N-Hydroxyphthalimide: Efficient and Selective Functionalization of Benzyl- and Allylic C−H Bonds

  Ji Min Lee, Eun Ju Park, Seung Hwan Cho, Sukbok Chang* 

  J. Am. Chem. Soc. 2008, 130, 7824-7825. 

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• Others

  Evaluation of Catalytic Activity of Copper Salts and their Removal Processes in the Three-Component Coupling Reactions

  Seung Jun Hwang, Seung Hwan Cho,Sukbok Chang* 

  Pure Appl. Chem. 2008, 80 (5), 873-879. 

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• Others

  Room Temperature Copper-Catalyzed 2-Functionalization of Pyrrole Rings by a Three-Component Coupling Reaction

  Seung Hwan Cho, Sukbok Chang* 

  Angew. Chem., Int. Ed. 2008, 47, 2836-2839. 

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• Others

  Copper-Catalyzed Three-Component Reaction of 1-Alkynes, Sulfonyl Azides, and Water: N-(4-Acetamidophenylsulfonyl)-2-phenylacetamide

  Seung Hwan Cho, Seung Jun Hwang, Sukbok Chang 

  Organic Syntheses 2008, 85, 131. 

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• Others

  Rate-Accelerated Nonconventional Amide Synthesis in Water: A Practical Catalytic Aldol-Surrogate Reaction

  Seung Hwan Cho, Sukbok Chang* 

  Angew. Chem., Int. Ed. 2007, 46, 1897-1900. 

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• Others

  Catalytic One-Pot Synthesis of Cyclic Amidines by Virtue of Tandem Reactions Involving Intramolecular Hydroamination Under Mild Conditions

  Sukbok Chang*; Min Jae Lee, Doo Young Jung, Eun Jeong Yoo, Seung Hwan Cho, Sun Kyu Han 

  J. Am. Chem. Soc. 2006, 128, 12366-12367. 

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• Others

  A Facile Access to N-Sulfonylimidates and their Synthetic Utility for the Transformations to Amidines and Amides

  Eun Jeong Yoo, Imhyuck Bae, Seung Hwan Cho, Hoon, Han, Sukbok Chang* 

  Org. Lett. 2006, 8, 1347-1350. 

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• Others

  Copper-Catalyzed Hydrative Amide Synthesis with Terminal Alkyne, Sulfonyl Azide, and Water

  Seung Hwan Cho, Eun Jeong Yoo, Imhyuck Bae, Sukbok Chang* 

  J. Am. Chem. Soc. 2005, 127, 16046-16047. 

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